# Conference overview

Mechanisms that shape cellular proteomes are critical for life. This conference focuses on the process of protein synthesis, from the molecular and structural understanding of the translational machinery to its regulation, its implications in cell and organismal biology, and its alteration in disease.

The regulation of mRNA translation is critical to maintain cell homeostasis and mediates cellular responses to environmental, physiological, and pathological cues. Given the central importance of protein synthesis, it is unsurprising that dysregulation or defects in mRNA translation are widely linked to disease, including cancer, neurological or metabolic disorders, and viral infection. In recent years, technical advances have challenged hitherto established dogmas, uncovered new quality control mechanisms, expanded the breath of translation regulators, enhanced our understanding of the dynamics of translation in living cells, and revealed unexpected interconnections with other cellular processes such as metabolism. Advances on these aspects of mRNA translation will be featured, as well as new insights into translation regulation in physiology and disease.

# Session Topics

- Initiation
- Ribosome/elongation/termination/quality control
- Methods/systems approaches
- Interconnections/turnover
- Metabolism/disease/viruses
- RNP complexes

This conference is partnered with Cold Spring Harbor Laboratory (CSHL).

Please see EMBL’s COVID-19 safety recommendations if attending the on-site event.

Please check out the following link for more information 
[HERE](https://www.embl.org/about/info/course-and-conference-office/events/trc23-01/#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2)

This conference will take place at EMBL Heidelberg, with the option to attend virtually.

Date: 6 - 10 Sep 2023,
Location: EMBL Heidelberg and Virtual,
Venue: EMBL Advanced Training Centre.

TRC23-01-Twitter-FB-Post.webp

Protein synthesis and translational control

 COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. (www.cost.eu) | The TRANSLACORE Cost Action is bridging disciplines and expertise across Europe in order to advance an emerging field in cancer biology: translational control in cancer. It is providing a unique opportunity to understand this biological process leading to reconsider our view of gene expression control in this disease and deliver novel therapeutic opportunities.

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Protein synthesis and translational control